一、 个人简介
庄伟建，教授，博导，美国加州大学Berkeley分校博士后，国际知名花生专家，福建省优秀专家，享受国务院津贴专家。福建农林大学豆科油料植物遗传与系统生物学中心主任，油料作物研究所所长。中国植物生物技术与产业化分会副会长，中国油料作物学会理事、植保学组副主任，福建省植物学会副理事长等。《The Plant Genome》等副主编、《Frontiers in Plant Science》特刊主编。主要从事植物基因组、分子与细胞生物学、植物基因工程和遗传与育种研究，先后主持国家基金面上或重点3项，863计划3项，支撑计划1项，科技部、农业部、财政部等重点和专项5项及省级科研项目共40余项。获省部科技一、二、三等奖6项，育成并推广新品种18个，获国家发明专利20余项，软件著作权和技术标准多项。新品种及新技术累计推广应用3000多万亩。在Nature Genetisc (2篇)、Plant Biotechnology Journal (3篇)、Critical Reviews in Biotechnology (1篇)、Journal of Experiment Botany (1篇)、J Integr Plant Biol. (2篇)、Frontiers in Plant Science (5篇)、Theory and Applied Genetics (3篇)、中国农业科学(3篇)等国内外刊物发表论文200余篇，参与编写著作2部。
二、 研究方向
1.豆科植物基因组与物种起源驯化
2.花生胚胎与种子发育分子机制
3.花生抗青枯病遗传与分子机制
4.花生抗黄曲霉分子机制与基因工程
5.花生种质创新及遗传与育种
6.花生种子科学与技术
三、 代表性成果（论文、专利、品种等）
1. Wang L, Chen H, Zhuang Y, Chen K, Zhang C, Cai T, Yang Q, Fu H, Chen X, Chitkineni A, Wang X, Varshney RK, Zhuang W.（*）. Multiple strategies, including 6mA methylation, affecting plant alternative splicing in allopolyploid peanut. Plant Biotechnol Journal, 2024 Jun;22(6):1681-1702. doi: 10.1111/pbi.14296.
2. Kun Chen,Yuhui Zhuang,Hua Chen,Taijie Lei,Mengke Li,Shanshan Wang,Lihui Wang,Huiwen Fu,Wenzhi Lu,Abhishek Bohra, Qiaoqiao Lai, Xiaolin Xu,Vanika Garg, Rutwik Barmukh, Biaojun Ji,Chong Zhang, Manish K. Pandey,Ronghua Tang, Rajeev K. Varshney, and Weijian Zhuang* A Ralstonia effector RipAU impairs peanut AhSBT1.7 immunity for pathogenicity via AhPME-mediated cell wall degradation.The Plant Journal, 2024, doi: 10.1111/tpj.17210.
3. Raza A, Chen H, Zhang C, Zhuang Y, Sharif Y, Cai T, Yang Q, Soni P, Pandey MK, Varshney RK, Zhuang W.（*）. Designing future peanut: the power of genomics-assisted breeding. Theor Appl Genet. 2024 Mar 4;137(3):66. doi: 10.1007/s00122-024-04575-3.
4. Sharif Y, Zhuang Y, Xie W, Zhang C, Chen K, Deng Y, Chen Y, Fu H, Wang L, Chen X, Zhuang W（*）, Chen H（*）. Molecular Cloning and Functional Identification of a Pericarp- and Testa-Abundant Gene's (AhN8DT-2) Promoter from Arachis hypogaea. Int J Mol Sci. 2024 Jul 12;25(14):7671. doi: 10.3390/ijms25147671. PMID: 39062915.
5. Weijian Zhuang, Rajeev Varshney主编. Book, 《Peanut genomics and biotechnology in breeding applications》. Frontier in Plant Science杂志社Press. 2023.
6. Yuxin Pan, Yuhui Zhuang, Tao Liu, Hua Chen, Lihui Wang, Rajeev K. Varshney, Weijian Zhuang* and Xiyin Wang*. Deciphering peanut complex genomes paves a way to understand its origin and domestication. Plant Biotechnology Journal,2023，21(11):2173-2181.
7. Sharif Y, Mamadou G, Yang Q, Cai T, Zhuang Y, Chen K, Deng Y, Khan SA, Ali N, Zhang C, Raza A, Chen H, Varshney RK, Zhuang W.（*）. Genome-Wide Investigation of Apyrase (APY) Genes in Peanut (Arachis hypogaea L.) and Functional Characterization of a Pod-Abundant Expression Promoter AhAPY2-1p. Int J Mol Sci. 2023 Feb 27;24(5):4622. doi: 10.3390/ijms24054622. PMID: 36902052
8. Zhuang Y, Sharif Y, Zeng X, Chen S, Chen H, Zhuang C, Deng Y, Ruan M, Chen S, Weijian Z. （*）. Molecular cloning and functional characterization of the promoter of a novel Aspergillus flavus inducible gene (AhOMT1) from peanut. Front Plant Sci. 2023 Feb 9;14:1102181. doi: 10.3389/fpls.2023.1102181. PMID: 36844094
9. Zhang C, Xie W, Fu H, Chen Y, Chen H, Cai T, Yang Q, Zhuang Y, Zhong X, Chen K, Gao M, Liu F, Wan Y, Pandey MK, Varshney RK, Zhuang W.（*）. Whole genome resequencing identifies candidate genes and allelic diagnostic markers for resistance to Ralstonia solanacearum infection in cultivated peanut (Arachis hypogaea L.). Front Plant Sci. 2023 Jan 4;13:1048168. doi: 10.3389/fpls.2022.1048168. PMID: 36684803
10. Yang Q, Sharif Y, Zhuang Y, Chen H, Zhang C, Fu H, Wang S, Cai T, Chen K, Raza A, Wang L, Zhuang W. (*). Genome-wide identification of germin-like proteins in peanut (Arachis hypogea L.) and expression analysis under different abiotic stresses. Front Plant Sci. 2023 Jan 23;13:1044144. doi: 10.3389/fpls.2022.1044144. PMID: 36756235; PMCID: PMC9901545.
11. Chong Zhang, Yuting Chen, Lihui Wang, Lu Liu, Xin Zhong, Panpan Chu, Meijia Gao, Hua Chen, Tiecheng Cai, Faqian Xiong, Xiurong Zhang, Ali Raza, Rong-long Pan, Rajeev K. Varshney, Fengzhen Liu*, Weijian Zhuang*. Genome-wide identification of papain-like cysteine protease family genes in cultivated peanut (Arachis hypogaea L.) and functional characterization of AhRD21B in response to chilling stress. Environmental and Experimental Botany,2023,209,105272
12. Ali Raza, Sidra Charagh, Benjamin Karikari, Rahat Sharif, Vivek Yadav, Muhammad Salman Mubarik, Madiha Habib, Yuhui Zhuang, Chong Zhang, Hua Chen, Rajeev K. Varshney, Weijian Zhuang（*）. miRNAs for crop improvement. Plant Physiology and Biochemistry,2023,201,107857.
13. Qiang Yang, Yasir Sharif, Yuhui Zhuang, Tiecheng Cai, Lihui Wang, Huiwen Fu, Wenzhi Lu, Min Ma, Huan Yang, Huaqi Li, Ali Raza, Chong Zhang, Hua Chen, Faqian Xiong, Weijian Zhuang（*）. Comprehensive in-silico characterization and expression analysis of UbiA prenyltransferase genes in peanut (Arachis hypogaea L.) against abiotic stresses.Plant Stress,2023, 10 (2023) 100229.
14. Raza A, Mubarik MS, Sharif R, Habib M, Jabeen W, Zhang C, Chen H, Chen ZH, Siddique KHM, Zhuang W（*）, Varshney RK. （*）. Developing drought-smart, ready-to-grow future crops. Plant Genome,2023，16(1):e20279.
15. Tiecheng Cai, Yasir Sharif, Yuhui Zhuang, Qiang Yang, XiangYu Chen, Kun Chen, Yuting Chen, Gao Meijia, Hao Dang, Yijing Pan, Ali Raza, Chong Zhang, Hua Chen, Weijian Zhuang*. In-silico identification and characterization of O-methyltransferase gene family in peanut (Arachis hypogaea L.) reveals their putative roles in development and stress tolerance. Frontiers in Plant Science, 2023，13,1048168.
16. Chen K, Zhuang Y, Wang L, Li H, Lei T, Li M, Gao M, Wei J, Dang H, Raza A, Yang Q, Sharif Y, Yang H, Zhang C, Zou H, Zhuang W*. Comprehensive genome sequence analysis of the devastating tobacco bacterial phytopathogen Ralstonia solanacearum strain FJ1003. Front. Genet. 2022，13:966092 doi: 10.3389/fgene.2022.966092
17. Chen H, Yang Q, Fu H, Chen K, Zhao S, Zhang C, Cai T, Wang L, Lu W, Dang H, Gao M, Li H, Yuan X, Varshney RK, Zhuang W*.Identification of key gene networks and deciphering transcriptional regulators associated with peanut embryo abortion mediated by calcium deficiency. Front. Plant Sci. 2022，13:814015.doi: 10.3389/fpls.2022.814015. "
18. Sharif Y, Chen H, Deng Y, Ali N, Khan SA, Zhang C, Xie W, Chen K, Cai T, Yang Q, Zhuang Y, Raza A, Zhuang W*. Cloning and functional characterization of a pericarp abundant expression promoter (AhGLP17-1P) from peanut (Arachis hypogaea L.).Front. Genet.2022，12:821281. doi: 10.3389/fgene.2021.821281
19. Cai T, Chen H, Yan L, Zhang C, Deng Y, Wu S, Yang Q, Pan R, Raza A, Chen S, Zhuang W*. The root‑specifc NtR12 promoter‑based expression of RIP increased the resistance against bacterial wilt disease in tobacco. Molecular Biology Reports. 2022，49:11503–11514doi：10.1007/s11033-022-07817-z "
20. Raza A, Tabassum J, Fakhar AZ, Sharif R, Chen H, Zhang C, Ju L, Fotopoulos V, Siddique KHM, Singh RK, Zhuang W*, Varshney RK. Smart reprograming of plants againstsalinity stress using modern biotechnological tools. Critical Reviews in Biotechnology, 2022，doi: 10.1080/07388551.2022.2093695."
21. Raza A, Tabassum J, Zahid Z, Charagh S, Bashir S, Barmukh R, Khan RSA, Barbosa F Jr, Zhang C, Chen H, Zhuang W*, Varshney RK.Advances in “Omics”approaches for improving toxic metals/metalloids tolerance in plants.Front. Plant Sci.2022，12:794373.doi: 10.3389/fpls.2021.794373"
22. Raza A, Sharif Y, Chen K, Wang L, Fu H, Zhuang Y, Chitikineni A, Chen H, Zhang C, Varshney RK, Zhuang W*. Genome-wide characterization of Ascorbate Peroxidase Gene Family in Peanut (Arachis hypogea L.) revealed their crucial role in growth and multiple stress tolerance.Front. Plant Sci. 2022，13:962182. doi: 10.3389/fpls.2022.962182
23. Raza A, Sharif Y, Chen K, Wang L, Fu H, Zhuang Y, Chitikineni A, Chen H, Zhang C, Varshney RK, Zhuang W*. Plant hormones and neurotransmitterinteractions mediate antioxidant defenses under induced oxidative stress in plants.Front. Plant Sci.2022，13:961872. doi: 10.3389/fpls.2022.961872"
24. Weijian Zhuang*, Xiyin Wang, Andrew H. Paterson, Hua Chen, Meng Yang, Chong Zhang, Pengchuan Sun, Yixiong Zheng, Lihui Wang, Wenping Xie, Wenting Chu, Huiwen Fu, Rajeev K. Varshney. Colinear gene similarities and repetitive DNA expansion reveal polyploid Arachis origin and novel evolution in plants---Reply to ‘Evaluating two different models of peanut’s origin’. Nature Genetics, 2020, http://dx.doi.org/.10.1038/s41588-020-0627-0.
25. Niaz Ali, Hua Chen, Chong Zhang, Shahid Ali Khan, Mamadou Gandeka, Dongyang Xie and Weijian Zhuang*. Ectopic expression of AhGLK1b (GOLDEN2-like transcription factor) in Arabidopsis confers dual resistance to fungal and bacterial pathogens. Genes, 2020, 11, 343; doi:10.3390/genes11030343.
26. Shahid Ali Khan, Hua Chen, Ye Deng, Yuhua Chen, Chong Zhang, Tiecheng Cai, Niaz Ali, Gandeka Mamadou, Dongyang Xie, Meng Yang, Baozhu Guo, Rajeev K Varshney and Weijian Zhuang*. High-density SNP map facilitates fine mapping of QTLs and candidate genes discovery for Aspergillus flavus resistance in peanut (Arachis hypogaea). Theory and Applied Genetics, 2020, DOI: 10.1007/s00122-020-03594-0.
27. Manish K Pandey, Arun K Pandey, Rakesh Kumar, Victor Nwosu, Baozhu Guo, Graeme Wright, Ramesh S. Bhat, Xiaoping Chen, Sandip K. Bera, Mei Yuan, Huifang Jiang, Issa Faye, Thankappan Radhakrishnan, Xingjun Wang, Xuanquiang Liang, Boshou Liao, Xinyou Zhang, Rajeev K Varshney, Weijian Zhuang*. Translational genomics for achieving higher genetic gains in post-genome era in groundnut. Theory and Applied Genetics, 2020, https://doi.org/10.1007/s00122-020-03592-2.
28. Soni P, Gangurde SS, Ortega-Beltran A, Kumar R, Parmar S, Sudini HK, Lei Y, Ni X, Huai D, Fountain JC, Njoroge S, Mahuku G, Radhakrishnan T, Zhuang W, Guo B, Liao B, Singam P, Pandey MK, Bandyopadhyay R, and Varshney RK. Functional Biology and Molecular Mechanisms of Host-Pathogen Interactions for Aflatoxin Contamination in Groundnut (Arachis hypogaea L.) and Maize (Zea mays L.). Frontiers of Microbiology. 2020. doi: 10.3389/fmicb.2020.00227.
29. Weijian Zhuang*, Hua Chen#, Meng Yang,…, Chong Zhang,…Rajeev Varshney, et al. The Arachis hypogaea genome elucidates legume karyotypes, polyploid evolution and crop domestication. Nature Genetics, 2019, 51(5): 865-876.
30. Chong Zhang, Hua Chen, Rui-Rong Zhuang, Yu-Ting Chen, Ye Deng, Tie-Cheng Cai, Shuai-Yin Wang, Qin-Zheng Liu, Rong-Hua Tang, Shi-Hua Shan, Rong-Long Pan, Li-Song Chen and Wei-Jian Zhuang*. Overexpression of the peanut CLAVATA1-like leucine-rich repeat receptor-like kinase AhRLK1, confers increased resistance to bacterial wilt in tobacco. Journal of Experiment Botany, 2019, 70(19):5407-5421
31. Sinha P, Bajaj P, Pazhamala LT, Nayak SN, Pandey MK, Chitikineni A., Huai D, Khan AW, Desai A, Jiang H, Zhuang Weijian, Guo B, Liao B, Varshney RK. Lekha Arachis hypogea gene expression atlas (AhGEA) for fastigiata subspecies of cultivated groundnut to accelerate functional and translational genomics applications. Plant Biotechnology Journal, 2020, https://doi.org/10.1111/pbi.13374
32. Pandey MK, Kumar R, Pandey AK, Soni P, Gangurde SS, Sudini HK, Fountain JC, Liao B, Desmae H, Okori P, Chen X, Jiang H, Mendu V, Falalou H, Njoroge S, Mwololo J, Guo B, Zhuang W-J, Wang X, Liang X, Varshney RK. Mitigating aflatoxin contamination in groundnut through a combination of genetic resistance and post-harvest management practices. Toxin, 2019, 11:315
33. Hua Chen, Qiang Yang, Kun Chen, Shanshan Zhao, Chong Zhang, Ronglong Pan, Tiecheng Cai, Ye Deng, Xingjun Wang, Yuting Chen, Wenting Chu, Wenping Xie and Weijian Zhuang*. Integrated microRNA and transcriptome profiling reveals a miRNA-mediated regulatory network of embryo abortion under calcium deficiency in peanut (Arachis hypogaea L.). BMC Genomics, 2019, 20:392
34. Shahid Ali Khan and Weijian Zhuang*. Obliging tactics to mitigate the intricate problem of aflatoxin contamination in peanut: A Review. Journal of Food Science & Technology, 2019,4(9): 986-1005
35. Fountain JC, Koh J, Pandey MK and Zhuang W, Chen ZY, Kemerait RC, Chen S, Varshney RK, Guo B (2018) Proteomic Profile of Aspergillus flavus responses to oxidative stress. Phytopathology 108:102
36. Ye Deng, Hua Chen, Chong Zhang, Tiecheng Cai, Bo Zhang, Shuangbiao Zhou, Jake Fountain, Ronglong Pan, Baozhu Guo, Weijian Zhuang*. Evolution and characterization of the AhRAF4 NB-ARC gene family induced by Aspergillus flavus inoculation and abiotic stresses in peanut. Plant Biology, 2018,20(4):737-750.
37. Fountain JC, Koh J, Yang L, Pandey MK, Nayak SN, Bajaj P, Zhuang WJ, Chen ZY, Kemerait RC, Lee RD, Chen S, Varshney RK, Guo B. Proteome analysis of Aspergillus flavus isolate-specific responses to oxidative stress in relationship to aflatoxin production capability. Sci Rep. 2018 Feb 21;8(1):3430. doi: 10.1038/s41598-018-21653-x.
38. Chong Zhang#, Hua Chen#, Tiecheng Cai, Ye Deng, Ruirong Zhuang, Ning Zhang, Yuanhuan Zeng, Yixiong Zheng, Ronghua Tang, Ronglong Pan and Weijian Zhuang*. Overexpression of a novel peanut NBS-LRR gene AhRRS5 enhances disease resistance to Ralstonia solanacearum in tobacco. Plant Biotechnology Journal, 2017,15(1):39-55.
39. Hua Chen#, Chong Zhang#, Tiecheng Cai, Ye Deng, Shuangbiao Zhou, Yixiong Zheng, Shiwei Ma, Ronghua Tang, Rajeev K. Varshney, WeiJian Zhuang*. Identification of low Ca2+ stress-induced embryo apoptosis response genes in Arachis hypogaea by SSH-associated library lift (SSHaLL). Plant Biotechnology Journal, 2016,14(2):682-698.
40. Yongli Zhao#, Chong Zhang#, Hua Chen, Mei Yuan, Rick Nipper, C. S. Prakash, Weijian Zhuang*, Guohao He*. QTL mapping for bacterial wilt resistance in peanut (Arachis hypogaea L.). Molecular Breeding, 2016, 36(2):1-11
41. Wang H, Khera P, Huang B, Yuan M, Katam R, Zhuang W, Harris-Shultz K, Moore KM, Culbreath AK, Zhang X, Varshney RK, Xie L, Guo B. Analysis of genetic diversity and population structure of peanut cultivars and breeding lines from China, India and the US using simple sequence repeat markers. J Integr Plant Biol. 2016, 58(5):452-65.
42. Fountain JC, Bajaj P, Pandey MK, Nayak SN, Yang L, Kumar V, Jayale AS, Chitikineni A, Zhuang W, Scully BT, Lee RD, Kemerait RC, Varshney RK*, Guo B (2016) Oxidative stress and carbon metabolism influence Aspergillus flavus transcriptome composition and secondary metabolite production. Scientific Reports 6, 38747; doi: 10.1038/ srep38747 (2016)
43. Pawan Khera, Manish K Pandey, Hui Wang, Suping Feng, Lixian Qiao, Albert K Culbreath, Sandip Kale, Jianping Wang, Weijian Zhuang, Rajeev K Varshney, Baozhu Guo. Mapping Quantitative Trait Loci of Resistance to Tomato Spotted Wilt Virus and Leaf Spots in a Recombinant Inbred Line Population of Peanut (Arachis Hypogaea L.) From SunOleic 97R and NC94022. PLoS One, 2016, 11 (7), e0158452
44. Zhang C, Pan S, Chen H, Cai T, Zhuang C, Deng Y, Zhuang Y, Zeng Y, Chen S, Zhuang W*.Characterization of NtREL1, a novel root-specific gene from tobacco, and upstream promoter activity analysis in homologous and heterologous hosts. Plant Cell Rep. 2016, 35(4):757-69.
45. 庄伟建,唐荣华，《中国花生栽培学》-（花生播种及苗期管理），上海科学技术出版社，上海，2003.12
46. 庄伟建.《作物种子学》-（花生）, 福建科技出版社,福建, 2001.7
四、 承担主要课题
1)花生抗曲霉基因工程及育种研究（2008DFA31150）；庄伟建主持，2008-2011年，科技部国际科技合作重点项目
2)抗青枯病相关基因克隆与转基因育种；庄伟建主持，2008-2011年，福建省烟草公司项目
3)高产优质抗黄曲霉花生新品种闽花6号示范推广；庄伟建主持，2009-2012年，科技部项目
4)抗青枯病相关基因克隆与转基因育种；庄伟建主持，2010-2013年，国家烟草局科研项目
5)基因工程改良花生油亚比（O/L）的研究（2008I0002）；庄伟建主持，2008-2010年，福建省科技厅项目
6)基因工程改良花生维生素E的研究（2009J01074）；庄伟建主持，2009-2011年，福建省科技厅项目
7)福建省作物分子与细胞生物学重点实验室（2008J1003）；庄伟建主持，2008-2011年，福建省科技平台建设项目
8)花生脂肪酸代谢相关基因的克隆与功能研究（2006AA10A114）；庄伟建主持，2006~2010年，国家863计划重大专项项目
9)花生抗病基因的克隆与功能研究（2006AA10A115）；庄伟建主持，2006~2010年，国家863计划重大专项项目
10)高产优质特用花生育种技术研究及新品种选育（2006BAD01A04）；庄伟建主持，2006-2010年，国家科技支撑计划（花生育种）课题项目
11)花生果种皮特异表达抗黄曲霉基因的载体构建与转达化研究（30571180）；庄伟建主持，2006~2008年，国家自然科学基金项目
12)花生闽花系列良种丰产栽培示范与推广；庄伟建主持，2007-2008年，国家财政部农业综合开发项目
13)烟草根特异表达启动子克隆与抗病基因在烟草根特异表达（国烟科[2006]371号）；庄伟建主持，2007~2011年，国家烟草局科研项目
14)高优、抗逆和专用型花生新品种选育研究（2006N0009）；庄伟建主持，2006~2008年，福建省科技计划项目
15)花生高产、优质、多抗与专用型品种的选育研究（2004N029）；庄伟建主持，2004~2007年，福建省科技计划项目
16)花生果种皮特异表达启动子克隆与真菌细胞壁水解酶基因抗黄曲霉遗传转化研究（2002I021）；庄伟建主持，2002~2006年，福建省科技厅国际合作重点项目
17)抗黄曲霉、丰产优质花生新品种种子基地建设（闽发改农业[2005]528号）；庄伟建主持，2006~2008年，福建省发展改革委员会项目
五、 教学情况
《作物高产栽培》
六、 招生方向
作物遗传育种
生物学
七、 联系方式
邮箱：weijianz1@163.com
